?????·??|?§???????é????????????o??o|è???o¤??????A??????????????????Dako????o§?????'é??è????-?????? PD-L1 IHC 22C3 pharmDx ???é??è??CE è?¤è?????è????1??????KEYTRUDA?????è?·?????¨???è?????é|???a??¨??¨??????é???°????è??è?o??? PD-L1 è?¨è?????????????1?3????KEYTRUDA????°?·2è????1????????oè???§???§é???°????è??è?o??? (NSCLC) ???????o??2????è????????KEYTRUDA?????é??????????????????????????????¤§?1??¤??????????/??°??o?§°??oé???2???????????o§??????PD-L1????3?è????????
è?????????±??????1??????è?? PD-L1 IHC 22C3 pharmDx ????????¨?o???a??????è???2????????1?????????¨?o??·2?????????è???2??????????PD-L1 è?¨è??????????????è???§???§ NSCLC ???è???????????è????-??? KEYTRUDA ??°?·2??1?????¨?o? PD-L1é??è?¨è?????TPS>50%??????è???§???§é???°????è??è?o??????è?????????o??2????????·2?????????è???2??????????PD-L1 è?¨è?????TPS> 1%??????è???§???§é???°????è??è?o??????è??????2??????? PD-L1 IHC 22C3 pharmDx ????-¤?????'??°?????3????????·???é???°'?13 PD-L1 è?¨è??????????a???è???2????????????????è???§???§ NSCLC ??????è?????é??è???-¤????????1?3???????????????????è?????KEYTRUDA ????????¨?????¨?-¤?1???????????¤§?¤???° NSCLC ???è???????????????o??2??????1?3???????????????????,PD-L1 IHC 22C3 pharmDx?1??????¨?o???¨?o??o???????????2????é??????????|???????????¨KEYTRUDA ???è?????è????°??? PD-L1 IHC 22C3 pharmDx ?????????????????????è??é???????o??1????o??2???????PD-1??????????3????é???°????è??è?o??????NSCLC??? ???è???????|?????????????????1?3???? ?????·??|è????-?????o???????-|?o????é?¨???è?? Jacob Thaysen è?'é?????a???????????é????' ?????¨??§?'2???PD-L1 IHC 22C3 pharmDx ???è??????±??????1???????????¨?o?è???§???§é???°????è??è?o??????è??????o??2??????1?3???????????????§?'2???????-|???é??è?? PD-L1 IHC 22C3 pharmDx ??????????????????è????????è??è????¤??-??? PD-L1 é????????è?¨è????????è?????è????¤?-|???è????o??1?????????è?????????????3?2??????1?3????a?? é??????????????éa???¤è????¤??????è???±?é???o§??????è??????2????é??????????? Roger Dansey ??????è°?é?????a?????????-|?????1???è??éa?è????????è???o§?????????è????????é???±????è?????????????'é??è????-?o§??????PD-L1 IHC 22C3 pharmDx????????°?????oè????¤?-|??????????o??????aè???????? PD-L1 è?¨è??é??????2????????????1?3???? KEYTRUDA ??°???è??????-?è?¨??? ???PD-L1 ??????é??è??é?'?????o?????????è??????2????????????????è?????è????¨é???°????è??è?o??????è???2??????-è?·é??è|?????????¨?????'é??è????-?o???¨è????'??1???????±?è?3??1????o??2?????????????????????3?????§?'2???è????¤?-|?????????????????'?¤????è?o??????è?????a?? è?o????????¨?????????????-??o???????è|??????????è?? NSCLC ???è????????è?o??????è????? 80%??? PD-L1 IHC 22C3 pharmDx ????????·??|?§???????é???????????é??????????? (Kenilworth, NJ, USA) ????????????????o§?????????è????? PD-1 ??????????3? KEYTRUDA ??????é???????? KEYTRUDA ???????§??oo?o??????????é???????????é??è?????????oo??????????3???????è?????????????????????????1???è????¤???è?????KEYTRUDA é????-?o? PD-1??? PDL1???????????3PD-1???é????????????????? PD-L1 ??? PD-L2 ?1?é?'???????o??????¨??????è??????'???3?????±???è????¤???è???1??????±???????o·???è????? T ?·??·'???è?????