?????·??|?§??????????????o??o|è???o¤??????A???è??????????????PD-L1??????è???????????????????????????-|?3???????è'§??· SK006?????°?·2è?·?????§???CE-IVDè?¤è??????????¨?o????é????????
PD-L1??????è???????????????????????????-|?3?????????¨?o???????è??????????????KEYTRUDA???????????????????????????2??????????é????????è??1???KEYTRUDA???????§?PD-1???????2????è??????????±é??????????????????????????????¤§?1??¤??????????/??°??o?§°??oé???2????????????????
??¨??§?'2???KEYTRUDA????????????????????¨???????????¨è'????????????????é????¨?o??2????è????¤è?¨è??PD-L1 [è?????é?3??§è????? (CPS) a?? 1] ????????-??§????¤??????§???è???§???§???é?????????oo???è??2???
PD-L1è?¨è?????????o?KEYTRUDA?-????PD-1????3??????3é????????????????????è???±?????3?????2??????·?????¨è?????è???¤???????????±??????-??????è????????
???é??????????¨?????3??§??-???????¤§???è§???????3???2020?1'??§?'2??°???è????????????o|??o30447???4???
?????·??|é???o§??????è?????è????-?????o???????-|?o????é?¨???è??Sam Rahaè?¨è?o?o?????±???¨?o????é???????|????????±?????????è?¨?¤o???a??KEYTRUDA ?-? PD-1/PD-L1é???????????????3??·2?????oè?????è???¤????è?????é??è|????????2????é????????é?????PD-L1??????è???????????????????????????-|?3??????¨??§?'2???é???o????????±???°???é???????????????-|?????????è?·??????é?????è????-???????????'?¤??????????è???°????????o?é??????2???????a??
?????????PD-L1??????è???????????????????????????-|?3???????è?·???CE-IVDè?¤è???????'é??è????-?o§????????¨?o???????è??????????????KEYTRUDA?2??????????é????????è?????PD-L1 CPS a?? 1??????
è?????é???o????????±?????????'?¤????è????????é??è??????????????????????|é?????KEYTRUDA????3?????1?è??????-??·???o?o??????·??|?????o???????????'??¨????????o?o?IHC???é????????????2????è????-??1é?????é???????°??????
KEYTRUDA?????é??????-???????é???2???????è??????3¨????????????
1 PD-L1 ??????è???????????????????????????-|?3????PD-L1 IHC 22C3 pharmDx [?????¨è?'???]????????????????|??°??o??·????????????????????????·??|?§???????é???????? (2022).
2 Keytruda [Summary of Product Characteristics]. European Medicines Agency (2022).
3 WHO. Cervical cancer, Key facts. (accessed May 09, 2022).
4 European Cancer Information System (ECIS), European Commission. Cervical cancer burden in EU-27. (accessed May 09, 2022).