The next generation of immune cell therapies requires a new generation of analysis tools
Develop a safe, potent, and persistent immune cell product by understanding immune cell function. Whether it be activation, proliferation, cell fate, cytotoxic killing, or immunomodulation, Agilent is dedicated to supporting your next-generation therapies with key technologies.
Breakthroughs in immunotherapy
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Measuring phenotype, potency, and persistence at all phases of development
Discovery
Translation
Production
Develop new immune cell therapies:
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Agilent SureGuide portfolio
Perform stable, on target CRISPR editing of immune cells to engineer highly specific cell therapies.
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Agilent xCELLigence RTCA and
Seahorse XF technologies
Assess and validate function, fate and fitness of immune cells on real time live-cell platforms that deliver relevant functional data.
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NovoCyte Quanteon flow cytometer
Establish actionable phenotypes at the benchtop for immune cell subsets including lineage and functional poise by multiparametric flow.
Understand the effects of immune cell therapies on a constantly evolving tumor microenvironment:
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Test gene edits and other interventional strategies for phenotype, potency, fitness, on/off target effects, and cell fate programming.
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Correlate relevant kinetic data to inhibitory effects such as exhaustion, anergy, and other escape phenotypes due to interactions with a constantly evolving tumor and its microenvironment.
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Sensitively measure live cell function and simultaneously scan the temporal components of an ever-evolving immune response in terms of efficacy, persistence, and safety.
Define key quality control attributes for cell therapy manufacturing:
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Seamlessly transition to SureGuide RNAs manufactured under GMP with the same expected quality and performance.
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Quantify the efficacy of cell therapies to better define key quality and process performance criteria with real-time potency assays.
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Generate reliable analytics for the quality control and release of compliant products.
Discover the Agilent immune cell therapy tool bench
Contact us today
Want to learn more about the Agilent immune cell therapy tool bench? Whether you would like to speak to an expert, request a demo, or simply request more information, we would be happy to connect with you.
For Research Use Only. Not for use in diagnostic procedures.