Immunology Research
Measure and tune the drivers of immune cell fate and function
Metabolism is intimately linked to many aspects of immune cell biology. Whether your research focuses on immune cell activation, expansion, differentiation, signaling or suppression, measuring the influence of metabolic programs on immune cell biology provides insight into how nutrients and pathways drive immune cell processes. Immunometabolism is a rapidly growing area of research, driving discovery of novel, innovative strategies to modulate and control immune cell fate and function. Agilent Seahorse XF technology provides tools to explore the upstream biology and cellular and molecular mechanisms controlling immune cell response through live cell, real-time metabolic analysis.
Learn about how immunologists are using Seahorse XF technology to:
- Quantify activation kinetics in a variety of immune cell types.
- Monitor metabolic phenotype and fitness.
- Measure immune cell life cycle, lineage, and checkpoints.
New approaches to immune cell activation T cell / Macrophage / Neutrophil
Uncover Agilent’s next generation of solutions for Immunotherapy
Visit the Agilent Cell Analysis Publications Database or Cell Reference Database to search for publications relevant to your research.
For Research Use Only. Not for use in diagnostic procedures.
Assessing functional metabolism using cells sourced from blood
- PDF/ Found In: Application Notes
- Date : 04 Jan 2017
- File Size : 643.12 KB
- Application Notes
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Automated Cell Fixing and Antibody Staining in Microplates
Here we describe the use of the 406 FX Washer Dispenser to automate the fixation and staining processes typically used prior to fluorescence imaging.- Application Notes
- English
- 06 Jun 2023
- 2.31 MB
Rapid Measurement of IgG Using Fluorescence Polarization
This application note describes the use of the Agilent BioTek Synergy Neo2 hybrid multimode reader to rapidly determine IgG concentrations.- Application Notes
- English
- 22 Feb 2023
- 372.45 KB
Real-time, multi-day cell stress assay: Quantifying the unfolded protein response using a non-toxic genetically-encoded fluorescent sensor, live cell imaging, and label-free cellular impedance
A demonstration of how the Agilent xCELLigence RTCA eSight real-time imaging platform can be used to monitor induction of the unfolded protein response using a genetically encoded fluorescent sensor.- Application Notes
- English
- 21 Apr 2021
- 4.44 MB
Real-Time Specificity and Potency Assessment of Human Papilloma Virus Specific Engineered T Cells
Using the Agilent xCELLigence RTCA system to assess both the selectivity and potency of the TCR-engineered TILs toward HLA restricted cells.- Application Notes
- English
- 21 Jul 2020
- 1.38 MB
Analysis of Phosphorylated STAT Protein Signaling in Lymphocytes Using Flow Cytometry
Examines the phosphorylation of signal transducer and activator of transcription (STAT) proteins in response to cytokine stimulation using a phosphoflow technique.- Application Notes
- English
- 02 Jul 2020
- 1.13 MB
Evaluating Changes in Cell Metabolism in Neuroimmune and Neuropsychiatric Disorders
Application Brief- summarizes scientific Agilent-Seahorse XF research focused on neurodegeneration, immunology, and infectious disease.- Application Notes
- English
- 17 May 2017
- 689.46 KB
Measuring glycolytic function in cells
Real-time, kinetic measurement of glycolysis connects energy pathways to cell growth and proliferation- Application Notes
- English
- 08 Mar 2017
- 1.07 MB
Assessing the impact of autophagy on cellular metabolism
Real-time, functional metabolic assays connect energy pathways and autophagy- Application Notes
- English
- 22 Dec 2016
- 1.06 MB
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Accelerating immunotherapy research– new discovery tools for measuring immune cell fate, fitness, and function
In this webinar, Dr. David Ferrick discusses how achieving a better understanding of immune cell metabolism has advanced cell therapies for cancer treatment. His presentation will focus on how to apply the newest XF Analyzer, the Agilent Seahorse XF HS Mini, for high-sensitivity cellular metabolic measurements in the immunotherapy field to deepen our understanding of how bioenergetics drives immune cell fate, fitness, and function. In addition, Dr. Ferrick will introduce a comprehensive workflow solution which has been optimized for high-sensitivity immune cell analysis designed to further propel immunotherapy discoveries.
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Energy Pathways Video
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