Agilent Home >
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Agilent News Hub ????????? >
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2024?1'1???5???
1985?1'??????????????°????????-??a???????¤? (JT) ?????????????°???2????¤?????????°???????????3???????o???-?????????????????§èa?????????????????????2???é??????'?9??2?????????????????°????o???-??????????????|????????¨??§????????·???éoo?????·????±3é?????????????·????????3????????????????????????èa???3????????-?????¨??????????·?é??????o???-??¨???????????¨???è??????????-?????¨?????????è???o???-??????é?2??o?????|???????????????è???????????????????|??????è???????????è???????oè|?????????????é??è|???a?????¤??1?????????????????1?????a????????3??° (HTS???é??é???¤§é????1?????a????????3??°???????'???¨?????|?????????JT???è???·????????????? ??????????????? ??¤è°· ?????? ???????????????????????????????°???????????¤???????è????????????????¤??1?????????????????1?????a????????3??°??a????????¤?????|???è?±?????????????????????????????????
??????1 ???????????°????????-??a???????¤? ???è???·?????????????
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JT??????è?????é??????o???-???????¤§????????????1987?1'????????¨??§?????????????§??-|??????è?????a??è2????a?¤???????????????è???§????????o·???è2???????????????????a??a??a??????????????????¤???????è???o???-?????2?????????????????1????-???¨????????????????°???§è?|??????????????-??????è???§??????????????????????JT??o?????a??a???????????°è??????±??????|??????è???§????????????§????????????????????¨??????????????§???????????¨??a?????|??????é????o???é?2?????|??????????????a??a???????????°è??????????o??????????????a???????????????????????????é????o????????§??????????¤?????????????30?1'??????1993?1'??????è???·?????????????????????????????????????é????o???????????·????????|??????????????????è???·???????????????????????-|???????????????????????????????????????è??????????????è????????????????????????????¨??§???????????a??????è¤???°???????????????????§??????????????·???????????????§?????????????-????è??????????1????????|??????????????¨??????????????a??°??¨???è??è????????è???????????????????????????????-?????????3é???????§??????é????o???é?2?????|?????????????????????????????§????????°è|????è3a???è???????????????-|???è??????-????è??????????¨?????????????????¨?????|??????????????¤è°·?°?????????????????????????????????|????????????????'?????????¤??1?????????????????1?????a????????3??°???è?????é?¨??2???????±??????|????????????
??????2 ???????????°????????-??a???????¤? ???è???·????????????? ??????????????? ??¤è°· ???????°?
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2012?1'???JT????????¨???????????¤??1???????????????è3aé??????????·??1???????????????????????3?????????????????-????????????Agilent RapidFire 360?????????è?°???è????????????????|???RapidFire????'???¨?????|??????????????????????????1?????a????????3??°????????????è??è??????¤?????????????????????§??????????????¨??a???????§??????a?????????é????a????????????????????¨????°???????è??????????????è???????|????????????2021?1'?????§???7????????2?????????????????????RapidFire 360???????????¨?????|????????¤è°·?°??????????384?????3?????????1???é????§??|?????§????????¨????????1???????????????????????????????????§?????????????????°?????3?????1?????a????????3??°??????????'???¨??????????????????3?????????????????1?????a????????3??°???2é?±é???¨??o|??§??????????????¨?????§????????????????????¨èa??????|????????????
??????3 Agilent RapidFire 360 ?????¤??1???????????????è3aé??????????·??1?????????2012?1'?°????
2021?1'???????????????????¨???????Agilent RapidFire 400?????¨è3aé????????è¨????Agilent 6495C??????????????????????????·??1?????????RapidFire-MS???????°?????????|?????????2023?1'?????§????????§???3????????2?????????????'?????'???¨?????|??????????????¤è°·?°????????????1????'°è??????????oè3a????¤????????¤???o??????è???????§??????è3aé????????è¨?????¤????è??????3???§????§???????é???????????RapidFire-MS?????¨???????????¨????????????????????????è??????3?????§???????????????¨?????§????????????????????????????????????????????????????§?é???'???§???é???????1?????????è????????????'???§?????????è2???????????????¨?????§????????????????????¨è?±?????|????????????????????????RapidFire 400?????§????????°??????1536??|??§???????????????????????????????????¨????????·??'???è????a?????3??????????????|??????????????-è???????|???????????¨????????????????????????????????3????????-????????????è3aé????????è???????¨???????????§?????1?????????????????¨??a??????????????????????????????????????|????????????
JT???è???·???????????????§10?1'????????????????????|RapidFire??????????????|???????????±????????§????????????????????3???????????§?¤??????oè3a????????????????¤???o??????è????a?????¨??????è??????12??????è?2????12???????????????????????¨??????è?????????????1?????????????????§????????????????????3???????????????????2??????????????????1????????????????????????????????|???????????¨??????????????????????????????????????3??????????????????è??????????????????????¨?????°?????¨é??????????????????????????????????a?????????é????????è3aé????????è¨??????????è¨-?????a????????¤?????|è3a??????????????¨????????o??aè???o??????????????????¨????????°è±??????????????????????????????3??3??????????????3?????????é??è?±??????????????§??????????????????????????¨????????????é???????????????????????????????¤è°·?°??????¨???è?±?????|????????????
RapidFire??§??????????????????????????a?????????é???????????è3aé????????è¨????è?|???????3¨??????????????¨??§é??é??????????3???????????¤???????????¤??3?????§?????·??§??3?????¨?????????????????????????????????????????¤??1?????????????????1?????a????????3??°???????o??????o????????¤è°·?°??????????1?????1?????a????????3??°??????1é????????è???????¨??a??????????????????????????a???é??é????????????????????????????¨è¨??????????????????????JT???è???·????????????? ???????????????????????¤??1?????????????????1?????a????????3??°?????°???????????§?????????RapidFire 400????????????????????|?????? Agilent 6495C????????????è¤???°??????????????????è3aé????????è¨??????????????????|????????????????????????????????????????3????????????|??1??§??????????????§????????????è±????????????|???RapidFire?????????è3aé????????è¨????????????§?????????????????????????????a?????¨????????????????????¨??¤è°·?°????è?±?????|????????????
??¤è°·?°???????RapidFire??????????'???¨??§?????????????????|???????????????????o¤????????'??????????????|???????????¨??????????????3?????????è¨??????|?????????????????????????????|????????????????????|???????????|?????|??????????????????è§?????3???a??????????????|???????????¨??±?????§????????°??????????????¨??§????????§????????|??????????????¨?????|???é???????-????????¤??a??????????????§??????
??????4 Agilent RapidFire 400 ?????¤??1???????????????è3aé??????????·??1??????
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è???1'??????è?????????????3????????????????????¤è°·?°??????°??????????????a?????????????????????é??è|??????a?????¨è???????|???????????????è?????????????§???????????°?????°???low hanging fruits ??????????±??????¨?????????????????|?????????????????????????????§???????????¤???????????|???????????|???????????¨è¨?????????????????°??????a???è??????????2?????????????????|????????????????????|????????????é????????????????2?????????????????¨???????????3??§??????é????????????????2????????????????????????????????????????????????????¨????è?????è3a???è§????TPD: Targeted Protein Degradation??????è?????è3a????o??????¨?????????è?????Protein Interaction Stabilizer????????±???????????§???????????¨???????????°??????????????a???????????????????????????é?2?????§?????????è3aé????????è¨?????'???¨????o??????????è|??????|???????????????????1'??????è??????????????è|???|????????¤è°·?°????????????¤??????è??????????°?????????è??????????????????????|????????|????????¨???????????¨?????????è?·?????|??????????????¤??????è???????????????????a???????????°???????????????????????|????????¨???????????3????????????????????¨??????è????????é??è|???§????????¨è?±????????????
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AI???????????°èa°???????????¨??????????????????è???????????è?????è|???¤????????????????????§???????????????????????¤è°·?°??????????TPD??a????????°?????a???è??????????a?????????è|???¤????????|???????????????????????a????????????????????????????????|????????¨?????????????????????????????a??a????????????????????a????????-????????§???è????????????????3??????è|???¤?????|?????????????????????è??????????3??1??????????????|???????????????????????¨?????a???????????3??1?????¨??????????????????????????????JT??o?????a??a???????????°è??????±??????|??????è???§????????????§????????????????????¨?????????????????¨è?±?????|????????????
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