游離 DNA ScreenTape 分析

Quality Control of Cell-free DNA samples Analyzed with Next-Generation Sequencing

The Sample Processing Lab (SPL) collaborated with the Genomics and Proteomics Core Facility (GPCF), both part of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) to track 13 cfDNA samples with the TapeStation system from initial QC with the %cfDNA metric, through the NGS workflow, to the final sequencing results.

• Application Notes
• English
• 09 Sep 2020
• 737.25 KB
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Detection of Contaminating High Molecular Weight DNA with the Cell-Free DNA ScreenTape Assay

In this technical overview, detection of contaminating high molecular weight DNA is discussed, comparing analyses between Bioanalyzer and TapeStation systems.

• Technical Overviews
• English
• 09 Aug 2023
• 702.69 KB
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Monitoring the Impact of Pre analytical Parameters on cfDNA Quality

Cell-free DNA has become an important source for potential new biomarkers. Yet, it represents a challenging sample type due to its low yield and complex fragment size distribution. Controlling and monitoring pre-analytical parameters, including cfDNA extraction, is crucial for experimental success A new automated electrophoresis assay was used to compare nine different kits tailored for cfDNA extraction.

• Posters
• English
• 17 Mar 2023
• 479.48 KB
• PDF