6546 LC/Q-TOF 和 1290 Infinity II HPLC
6546 LC/Q-TOF
6546 高分辨率質譜通過全面的工作流程，提升實驗室在代謝組學研究、食品安全、食品真偽檢測和環境篩查方面的分析能力。其同時具備出色的靈敏度、動態范圍、分辨率、同位素保真度和精確質量測量，所得高質量數據可為快速、簡化的數據審查流程提供滿足您需求的可信度。
采用 Q-RAI（四極桿分辨全離子）或全離子采集功能后，現可將食品安全篩查與片段信息結合用于鑒定，讓您執行目標物和疑似物的同步篩查。此外，高分辨率、寬動態范圍與高同位素保真度使 6546 LC/Q-TOF 成為了代謝組學研究的理想平臺。
采用 Q-RAI（四極桿分辨全離子）或全離子采集功能后，現可將食品安全篩查與片段信息結合用于鑒定，讓您執行目標物和疑似物的同步篩查。此外，高分辨率、寬動態范圍與高同位素保真度使 6546 LC/Q-TOF 成為了代謝組學研究的理想平臺。
- Quadrupole Time of Flight LC/MS
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Product Details
Features
- 同時提供 5 個數量級的譜內動態范圍以及超過 60000（高質量數）和超過 30000（低質量數）的質量分辨率，不論分析物濃度高低，均能獲得可靠結果
- 亞 ppm 級的質量數準確度和 5% 以內的同位素保真度，有利于未知物鑒定時縮小可能化合物的范圍
- 體驗無需放空即可維護離子源和進樣口的方便快捷
- 通過農藥、獸藥、真菌毒素、可萃取物與可浸出物以及水污染物的精確質量譜庫，擺脫了化合物數量和耗時的方法維護對靶向篩查分析的限制
- 訪問用于代謝譜、脂質組學和定性代謝流分析的代謝組學工作流程
- 使用最新的食品真偽檢測工作流程，簡化了食品原產地和食品摻假分析流程
Specifications
| MS 靈敏度（正離子） |
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| MS 質量準確度（正離子） |
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| MS 質量準確度（負離子） |
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| MS 采集速率 |
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| MS/MS 靈敏度（正離子） |
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| MS/MS 質量準確度（正離子） |
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| MS/MS 質量準確度（負離子） |
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| MS/MS 采集速率 |
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| TOF 質量分辨率 (FWHM) |
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| TOF 質量范圍 |
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| 同位素保真度 |
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| 四極桿分離質量范圍 |
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| 四極桿分辨率 (FWHM) |
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| 支持的附加軟件 |
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| 無需放真空的維護 |
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| 極性切換占空比 |
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| 溫度質量穩定性 |
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| 離子源 |
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| 譜圖內動態范圍 |
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| 軟件平臺 |
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Technology
How It Works
Applications
Literature
- Key Literature
-
Non-Target PFAS Analysis in Dried Blood Spots Using the Agilent 6546 LC/Q-TOF with Profinder and FluoroMatch
This application note demonstrates the use of FluoroMatch Suite for the analysis and identification of per- and polyfluorinated substances (PFAS) using an Agilent1290 Infinity II LC and Agilent 6546 LC/Q-TOF mass spectrometer with iterative exclusion (IE).- Application Notes
- English
- 13 Mar 2024
- 999.21 KB
Extracellular Flux Analysis and 13C Stable-Isotope Tracing Reveals Metabolic Changes
Combining real-time extracellular flux information with 13C stable?isotope?tracing allows greater insight into the mechanism of macrophage activation.- Application Notes
- English
- 16 Apr 2020
- 733.53 KB
Drug Screening in Whole Blood Using the Agilent 6546 LC/Q-TOF and the LC Screener Tool with Automated Sample Preparation
This application note describes a method for the routine screening of drugs and their related metabolites in whole blood, using the 6546 LC/Q-TOF and Bravo automated linquid handling platform.- Application Notes
- English
- 18 Mar 2022
- 2.16 MB
- Application Notes
- Brochures
- Case Studies
- Flyers
- Posters
- Technical Overviews
- White Papers
Support
- Support
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MassHunter Data Acquisition for LC/TOF and LC/Q-TOF Familiarization Guide
This guide teaches you how to use your MassHunter Data Acquisition for Agilent LC/TOF or LC/Q-TOF system.- Familiarization Checklists
- English
- 13 Jul 2023
- 4.44 MB
MassHunter Workstation 11.0 for LC/TOF and LC/Q-TOF Installation Guide
This book provides instructions to install the MassHunter Workstation software in these configurations: ? Workstation (standalone, no content management) ? Networked Workstation (networked, with content management on separate server)- Installation Guides
- English
- 13 Jul 2023
- 967.69 KB
MassHunter Networked Workstation Functional Design Specifications
This document contains the Functional Design Specifications for your Agilent MassHunter Networked Workstation system.- Specifications
- English
- 17 Nov 2022
- 13.06 MB
- Quick Reference Guides
- Site Preparation Checklists
- Supplemental Information
- User Manuals
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Customer Testimonials
Nicola Zamboni, PhD
ETH Zurich, Switzerland“與之前的 TOF 相比，6546 系統是一次重大進步，主要是由于它能在各種條件（速度、質量數范圍、強度）下實現動態范圍與出色分辨率的完美結合。對我們來說，6546 系統將成為我們應對挑戰性應用的理想儀器，如 13C 代謝流分析、高通量質譜和代謝物鑒定。”
View MoreVideos
Training & Events
The PFAS legacy in our urban environment
Per- and polyfluoroalkyl substances (PFAS) are emerging contaminants attracting global scientific and regulatory attention due to their environmental persistence and bioaccumulative properties.
Webinar/Training
Rapid Identification of Unknowns in Blackwater Using LC/QTOF-MS/MS
Liquid chromatography/quadrupole time-of-flight mass spectrometry with data dependent and independent analysis was used to identify target, suspect, and unknown compounds in aqueous leachate of wildfire ash and blackwater samples from the largest wildfire in Colorado history.
Webinar/Training
High-throughput LC-MS analysis to systematically map gut microbiome drug metabolism
Individuals vary widely in their drug responses, which can be dangerous and expensive due to significant treatment delays and adverse effects.
Webinar/Training
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