Cell Metabolism
Cell Metabolism
Mitochondrial dysfunction is commonly implicated in a range of diseases, including neurodegenerative disease and metabolic disorders relating to aging, obesity, and diabetes. With the advent of novel and sensitive analytical tools to measure dysfunctional metabolism, researchers are now utilizing metabolic measurements to advance therapeutic strategies. Agilent Cell Analysis provides sensitive measures for looking at the genes, proteins, and pathways that may be promising targets in drug discovery. Advance your research and discover target identification/validation, mechanism of action, substrate dependencies, toxicity, and drug efficacy for live cells in real time with a diverse portfolio of applications from Agilent Cell Analysis.
Discover Agilent Seahorse XF Applications in Cancer Metabolism.
Learn more about How Seahorse XF Technology Works.
Learn more about MitoXpress & pH-Xtra Products.
Search scientific publications that reference and/or cite Agilent Cell Analysis products.
For Research Use Only. Not for use in diagnostic procedures.
Illuminating the Cellular and Molecular Response to Drug Treatment by Combining Bioenergetic Measurements with LC/MS Omics
- PDF/ Found In: Application Notes
- Date : 01 Aug 2024
- File Size : 2.99 MB
Rapid Bioenergetic Functional Screening of Anticancer Drug Candidates
- PDF/ Found In: Application Notes
- Date : 30 Jan 2023
- File Size : 1.58 MB
Metabolic Profiling of Cells in 3D Cultures using MitoXpress Xtra and pH-Xtra Assays
- PDF/ Found In: Application Notes
- Date : 14 Aug 2020
- File Size : 875.55 KB
- Application Notes
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Illuminating the Cellular and Molecular Response to Drug Treatment by Combining Bioenergetic Measurements with LC/MS Omics
Cellular-resolution Agilent Seahorse XF bioenergetic analyses were combined with molecular-resolution Agilent Revident Q-TOF LC/MS to investigate adaptations in cancer cells.- Application Notes
- English
- 01 Aug 2024
- 2.99 MB
Rapid Bioenergetic Functional Screening of Anticancer Drug Candidates
This application note introduces a workflow that uses the XF Real-Time ATP rate assay data for identifying metabolic modulator and drug targets.- Application Notes
- English
- 30 Jan 2023
- 1.58 MB
Metabolic Profiling of Cells in 3D Cultures using MitoXpress Xtra and pH-Xtra Assays
Two workflows using MitoXpress Xtra and pH-Xtra probes to investigate cell metabolism in intact RAFT 3D collagen structures on fluorescent plate readers.- Application Notes
- English
- 14 Aug 2020
- 875.55 KB
Extracellular Flux Analysis and 13C Stable-Isotope Tracing Reveals Metabolic Changes
Combining real-time extracellular flux information with 13C stable?isotope?tracing allows greater insight into the mechanism of macrophage activation.- Application Notes
- English
- 16 Apr 2020
- 733.53 KB
Glycolytic Suppression - The Impact of Metabolic Modulation on Neural Stem Cell Fate
This application note highlights the affect that carbon source modification has on deriving neural cell lineages from stem cells.- Application Notes
- English
- 20 Jun 2019
- 1.68 MB
Direct Measurements of Cellular Metabolism for Identification of Mitochondrial Drug Targets
An overview of how the Agilent Seahorse XF Cell Mito Stress Test and XF PMP workflows can be applied to mitochondrial and metabolic target identification studies.- Application Notes
- English
- 10 Jun 2019
- 389.41 KB
High Spatial resolution FTIR imaging of biomedical tissue samples using a novel method of magnification enhancement
Application note for High Spatial resolution FTIR imaging of biomedical tissue samples using a novel method of magnification enhancement- Application Notes
- English
- 27 Feb 2018
- 2.52 MB
Evaluating Changes in Cell Metabolism in Neuroimmune and Neuropsychiatric Disorders
Application Brief- summarizes scientific Agilent-Seahorse XF research focused on neurodegeneration, immunology, and infectious disease.- Application Notes
- English
- 17 May 2017
- 689.46 KB
Measure Mitochondrial Respiration in Skeletal Muscle Fibers with a Seahorse Analyzer
Measuring Mitochondrial Respiration in Intact Skeletal Muscle Fibers with an Agilent Seahorse XF24/XFe24 Analyzer- Application Notes
- English
- 22 Dec 2016
- 1.07 MB
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