Seahorse XF Plasma Membrane Permeabilizer
The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.
- XF Assay Kits, Reagents & Cell Assay Media
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Product Details
Features
- Selectively targets the cellular plasma membrane for permeabilization
- Study mitochondrial function without isolating mitochondria
- 1.0 nM works for most cell types, meaning that minimal optimization is required
- The XF PMP reagent provides consistent results in every assay
Technology
Automatic measurement of energy metabolism in real time
Agilent Seahorse XF Analyzers measure oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of live cells in a multi-well plate, interrogating key cellular functions such as mitochondrial respiration and glycolysis. Seahorse XF Analyzers perform compound addition and mixing, label-free analytical detection, and automatic measurement of OCR and ECAR in real time. Learn MoreHow It Works
Literature
- Application Notes
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Direct Measurements of Cellular Metabolism for Identification of Mitochondrial Drug Targets
An overview of how the Agilent Seahorse XF Cell Mito Stress Test and XF PMP workflows can be applied to mitochondrial and metabolic target identification studies.- Application Notes
- English
- 10 Jun 2019
- 389.41 KB
- Flyers
- Posters
- Technical Overviews
Support
- Material Safety Data Sheets
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Seahorse XF Plasma Membrane Permeabilizer, Part Number 102504-100
Material Safety Data Sheet- Material Safety Data Sheets
- English
- 19 Apr 2022
- 132.02 KB
- User Manuals
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Tools
Agilent Seahorse XF Instruments Selection Guide
Evaluate and compare the Seahorse XF Analyzers.Agilent Cell Analysis Publication Database
Search scientific publications by research area, cell type and more.Seahorse XF Assay Learning Center
Up-to-date information on protocols and procedures for preparing, running, and analyzing an XF assay.Training & Events
Agilent Cell Analysis Webinar Series
View informative Agilent Cell Analysis Technology webinars on a variety of research subjects.
Webinar/Training
News
The Agilent Seahorse XF Pro platform
Transforming Bioenergetics - Again. Featuring new pharma-oriented workflow solutions with improved precision, along with advanced experimental design and analysis tools, you can optimize your workflow from start to finish.- 17 Jan 2022
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